Download Excel File List of Human Hormones

Eicosanoid,,,,,,,,,,,,,,,,SNo,Name,Abbreviation,Tissue,Cells,Receptor,Target Tissue,Effect,1,Prostaglandins,PG,seminal vesicle,,prostaglandin receptor,,,2,Leukotrienes,LT,,white blood cells,G protein-coupled receptors,,,3,Prostacyclin,PGI2,endothelium,,prostacyclin receptor,,,4,Thromboxane,TXA2,,platelets,thromboxane receptor,,,,,,,,,,,Peptide,,,,,,,,,,,,,,,,SNo,Name,Abbreviation,Tissue,Cells,Receptor,Target Tissue,Effect,1,Amylin (or Islet Amyloid Polypeptide),IAPP,pancreas,pancreatic ?-cells,amylin receptor,,"slowing down gastric emptying, inhibition of digestive secretion, and reducing food intake",2,Antimullerian hormone (or Mllerian inhibiting factor or hormone),AMH,testes,Sertoli cell,AMHR2,,Inhibit release of prolactin and TRH from anterior pituitary,3,Adiponectin,Acrp30,adipose tissue,,adiponectin receptors,,,4,Adrenocorticotropic hormone (or corticotropin),ACTH,anterior pituitary,corticotrope,ACTH receptor ? cAMP,,synthesis of corticosteroids (glucocorticoids and androgens) in adrenocortical cells,5,Angiotensinogen and angiotensin,AGT,liver,,angiotensin receptor ? IP3,,vasoconstriction,,,,,,,,,,,,,,,,release of aldosterone from adrenal cortex dipsogen.,6,"Antidiuretic hormone (or vasopressin, arginine vasopressin)",ADH,posterior pituitary,Parvocellular neurosecretory neurons in hypothalamus,several,,retention of water in kidneys,,,,,Magnocellular neurosecretory cells in posterior pituitary,,,moderate vasoconstriction,,,,,,,,Release ACTH in anterior pituitary,7,Atrial-natriuretic peptide (or atriopeptin),ANP,heart,,ANP receptor ? cGMP,,,8,Brain natriuretic peptide,BNP,heart,Cardiac myocytes,NPR,,(To a minor degree than ANP) reduce blood pressure by:,,,,,,,,,,,,,,,,"reducing systemic vascular resistance, reducing blood water, sodium and fats",9,Calcitonin,CT,thyroid gland,parafollicular cell,CT receptor ? cAMP,,"Construct bone, reduce blood Ca2+",10,Cholecystokinin,CCK,duodenum,,CCK receptor,,Release of digestive enzymes from pancreas,,,,,,,,Release of bile from gallbladder,,,,,,,,Hunger suppressant,11,Corticotropin-releasing hormone,CRH,hypothalamus,,CRF1 ? cAMP,,Release ACTH from anterior pituitary,12,Enkephalin,,Kidney,Chromaffin cells,Opioid receptor,,Regulate pain,13,Endothelin,,Stomach,X cells,ET receptor,,Smooth muscle contraction of stomach,14,Erythropoietin,EPO,kidney,Extraglomerular mesangial cells,EpoR,,Stimulate erythrocyte production,15,Follicle-stimulating hormone,FSH,anterior pituitary,gonadotrope,FSH receptor ? cAMP,,In female: stimulates maturation of Graafian follicles in ovary.,,,,,,,,,,,,,,,,"In male: spermatogenesis, enhances production of androgen-binding protein by the Sertoli cells of the testes",16,Galanin,GAL,central nervous system and gastrointestinal tract,,"GALR1, GALR2, and GALR3",,modulation and inhibition of action potentials in neurons,17,Gastrin,GRP,"stomach, duodenum",G cell,CCK2,,Secretion of gastric acid by parietal cells,18,Ghrelin,,stomach,P/D1 cell,ghrelin receptor,,"Stimulate appetite,",,,,,,,,,,,,,,,,secretion of growth hormone from anterior pituitary gland,19,Glucagon,GCG,pancreas,alpha cells,Glucagon receptor ? cAMP,,glycogenolysis and gluconeogenesis in liver,,,,,,,,,,,,,,,,increases blood glucose level,20,Gonadotropin-releasing hormone,GnRH,hypothalamus,,GnRH receptor ? IP3,,Release of FSH and LH from anterior pituitary.,21,Growth hormone-releasing hormone,GHRH,hypothalamus,,GHRH receptor ? IP3,,Release GH from anterior pituitary,22,Human chorionic gonadotropin,hCG,placenta,syncytiotrophoblast cells,LH receptor ? cAMP,,promote maintenance of corpus luteum during beginning of pregnancy,,,,,,,,,,,,,,,,"Inhibit immune response, towards the human embryo.",23,Human placental lactogen,HPL,placenta,,,,increase production of insulin and IGF-1,,,,,,,,,,,,,,,,increase insulin resistance and carbohydrate intolerance,24,Growth hormone,GH or hGH,anterior pituitary,somatotropes,GH receptor,,stimulates growth and cell reproduction,,,,,,,,,,,,,,,,Release Insulin-like growth factor 1 from liver,25,Inhibin,,"testes, ovary, fetus",Sertoli cells of testes,anterior pituitary,,Inhibit production of FSH,,,,,granulosa cells of ovary,,,,,,,,trophoblasts in fetus,,,,26,Insulin,INS,pancreas,beta cells,"insulin receptor, IGF-1, IGF-2",,"Intake of glucose, glycogenesis and glycolysis in liver and muscle from blood",,,,,,,,,,,,,,,,intake of lipids and synthesis of triglycerides in adipocytes Other anabolic effects,27,Insulin-like growth factor (or somatomedin),IGF,liver,Hepatocytes,"insulin receptor, IGF-1",,insulin-like effects,,,,,,,,,,,,,,,,regulate cell growth and development,28,Leptin,LEP,adipose tissue,,LEP-R,,decrease of appetite and increase of metabolism.,29,Lipotropin,LPH,anterior pituitary,Corticotropes,,,"lipolysis and steroidogenesis,",,,,,,,,stimulates melanocytes to produce melanin,30,Luteinizing hormone,LH,anterior pituitary,gonadotropes,LHR ? cAMP,,In female: ovulation,,,,,,,,,,,,,,,,In male: stimulates Leydig cell production of testosterone,31,Melanocyte stimulating hormone,MSH or ?-MSH,anterior pituitary/pars intermedia,Melanotroph,melanocortin receptor ? cAMP,,melanogenesis by melanocytes in skin and hair,32,Motilin,MLN,Small intestine,,Motilin receptor,,stimulates gastric activity,33,Orexin,,hypothalamus,,"OX1, OX2",,"wakefulness and increased energy expenditure, increased appetite",34,Oxytocin,OXT,posterior pituitary,Magnocellular neurosecretory cells,OXT receptor ? IP3,,release breast milk,,,,,,,,,,,,,,,,"Contraction of cervix and vagina Involved in orgasm, trust between people. and circadian homeostasis (body temperature, activity level, wakefulness).",35,Pancreatic polypeptide,,Pancreas,PP cells,pancreatic polypeptide receptor 1,,Self-regulation of pancreatic secretions (endocrine and exocrine). It also affects hepatic glycogen levels and gastrointestinal secretions.,36,Parathyroid hormone,PTH,parathyroid gland,parathyroid chief cell,PTH receptor ? cAMP,,increase blood Ca2+:,,,,,,,,,,,,,,,,indirectly stimulate osteoclasts,,,,,,,,Ca2+ reabsorption in kidney,,,,,,,,activate vitamin D,,,,,,,,,,,,,,,,(Slightly) decrease blood phosphate:,,,,,,,,,,,,,,,,(decreased reuptake in kidney but increased uptake from bones,,,,,,,,activate vitamin D),,,,,,,,,37,Prolactin,PRL,"anterior pituitary, uterus",lactotrophs of anterior pituitary,PRL receptor,,milk production in mammary glands,,,,,Decidual cells of uterus,,,sexual gratification after sexual acts,38,Prolactin releasing hormone,PRH,hypothalamus,,,,Release prolactin from anterior pituitary,39,Relaxin,RLN,uterus,Decidual cells,RLN receptor,,Unclear in humans,40,Renin,,Kidney,Juxtaglomerular cells,,,Activates the renin-angiotensin system by producing angiotensin I of angiotensinogen,41,Secretin,SCT,duodenum,S cell,SCT receptor,,"Secretion of bicarbonate from liver, pancreas and duodenal Brunner's glands",,,,,,,,,,,,,,,,Enhances effects of cholecystokinin Stops production of gastric juice,42,Somatostatin,SRIF,"hypothalamus, islets of Langerhans, gastrointestinal system",delta cells in islets,Somatostatin receptor,,Inhibit release of GH and TRH from anterior pituitary,,,,,Neuroendocrince cells of the Periventricular nucleus in hypothalamus,,,"Suppress release of gastrin, cholecystokinin (CCK), secretin, motilin, vasoactive intestinal peptide (VIP), gastric inhibitory polypeptide (GIP), enteroglucagon in gastrointestinal system",,,,,,,,Lowers rate of gastric emptying,,,,,,,,,,,,,,,,Reduces smooth muscle contractions and blood flow within the intestine,,,,,,,,Inhibit release of insulin from beta cells,,,,,,,,Inhibit release of glucagon from alpha cells,,,,,,,,Suppress the exocrine secretory action of pancreas.,,,,,,,,,43,Thrombopoietin,TPO,"liver, kidney, striated muscle",Myocytes,TPO receptor,megakaryocytes,produce platelets,44,Thyroid-stimulating hormone (or thyrotropin),TSH,anterior pituitary,thyrotropes,Thyrotropin receptor ? cAMP,thyroid gland,secrete thyroxine (T4) and triiodothyronine (T3),45,Thyrotropin-releasing hormone,TRH,hypothalamus,Parvocellular neurosecretory neurons,TRHR ? IP3,anterior pituitary,Release thyroid-stimulating hormone (primarily),,,,,,,,Stimulate prolactin release,,,,,,,,,Steroid,,,,,,,,,,,,,,,,SNo,Chemical class,Name,Abbreviation,Tissue,Cells,Receptor,Target Tissue,Effect1,androgen,Testosterone,,testes,Leydig cells,AR,,"libido, Anabolic: growth of muscle mass and strength, increased bone density, growth and strength,",,,,,,,,,,,,,,,,"Virilizing: maturation of sex organs, formation of scrotum, deepening of voice, growth of beard and axillary hair."2,androgen,Dehydroepiandrosterone,DHEA,"testes, ovary, kidney",Zona fasciculata and Zona reticularis cells of kidney,AR,,"Virilization, anabolic",,,,,theca cells of ovary,,,,,,,,Leydig cellss of testes,,,3,androgen,Androstenedione,,"adrenal glands, gonads",,AR,,Substrate for estrogen4,androgen,Dihydrotestosterone,DHT,multiple,,AR,,"5-DHT or DHT is a male reproductive hormone that targets the prostate gland, bulbourethral gland, seminal vesicles, penis and scrotum and promotes growth/mitosis/cell maturation and differentiation. Testosterone is converted to 5-DHT by 5alpha-reductase, usually with in the target tissues of 5-DHT because of the need for high concentrations of 5-dht to produced the physiological effects."5,mineralocorticoid,Aldosterone,,adrenal cortex (zona glomerulosa),,MR,,Increase blood volume by reabsorption of sodium in kidneys (primarily),,,,,,,,,,,,,,,,Potassium and H+ secretion in kidney.6,estrogen,Estradiol,E2,"females: ovary, males testes","females: granulosa cells, males: Sertoli cell",ER,,Females:,,,,,,,,,,,,,,,,Structural:,,,,,,,,,,,,,,,,promote formation of female secondary sex characteristics,,,,,,,,accelerate height growth,,,,,,,,accelerate metabolism (burn fat),,,,,,,,reduce muscle mass,,,,,,,,stimulate endometrial growth,,,,,,,,increase uterine growth,,,,,,,,maintenance of blood vessels and skin,,,,,,,,"reduce bone resorption, increase bone formation",,,,,,,,,,,,,,,,Protein synthesis:,,,,,,,,,,,,,,,,increase hepatic production of binding proteins,,,,,,,,,,,,,,,,Coagulation:,,,,,,,,,,,,,,,,"increase circulating level of factors 2, 7, 9, 10, antithrombin III, plasminogen",,,,,,,,increase platelet adhesiveness,,,,,,,,,,,,,,,,"Increase HDL, triglyceride, height growth Decrease LDL, fat deposition Fluid balance:",,,,,,,,,,,,,,,,salt (sodium) and water retention,,,,,,,,increase growth hormone,,,,,,,,"increase cortisol, SHBG",,,,,,,,,,,,,,,,Gastrointestinal tract:,,,,,,,,,,,,,,,,reduce bowel motility,,,,,,,,increase cholesterol in bile,,,,,,,,,,,,,,,,Melanin:,,,,,,,,,,,,,,,,"increase pheomelanin, reduce eumelanin",,,,,,,,,,,,,,,,Cancer: support hormone-sensitive breast cancers Suppression of production in the body of estrogen is a treatment for these cancers.,,,,,,,,,,,,,,,,Lung function:,,,,,,,,,,,,,,,,promote lung function by supporting alveoli.,,,,,,,,,,,,,,,,Males: Prevent apoptosis of germ cells7,estrogen,Estrone,,ovary,"granulosa cells, Adipocytes",ER,,8,estrogen,Estriol,E3,placenta,syncytiotrophoblast,ER,,9,glucocorticoid,Cortisol,,adrenal cortex (zona fasciculata and zona reticularis cells),,GR,,Stimulation of gluconeogenesis,,,,,,,,,,,,,,,,Inhibition of glucose uptake in muscle and adipose tissue Mobilization of amino acids from extrahepatic tissues Stimulation of fat breakdown in adipose tissue anti-inflammatory and immunosuppressive10,progestogen,Progesterone,,"ovary, adrenal glands, placenta (when pregnant)",Granulosa cells theca cells of ovary,PR,,Support pregnancy:,,,,,,,,,,,,,,,,Convert endometrium to secretory stage,,,,,,,,Make cervical mucus permeable to sperm,,,,,,,,"Inhibit immune response, e.g. towards the human embryo.",,,,,,,,Decrease uterine smooth muscle contractility,,,,,,,,Inhibit lactation,,,,,,,,Inhibit onset of labor,,,,,,,,Support fetal production of adrenal mineralo- and glucosteroids,,,,,,,,,,,,,,,,Other:,,,,,,,,,,,,,,,,Raise epidermal growth factor-1 levels,,,,,,,,Increase core temperature during ovulation,,,,,,,,Reduce spasm and relax smooth muscle (widen bronchi and regulate mucus),,,,,,,,Antiinflammatory. Regulate immune response,,,,,,,,Reduce gall-bladder activity,,,,,,,,"Normalize blood clotting and vascular tone, zinc and copper levels, cell oxygen levels, and use of fat stores for energy",,,,,,,,Assist in thyroid function and bone growth by osteoblasts,,,,,,,,"Resilience in bone, teeth, gums, joint, tendon, ligament and skin healing by regulating collagen",,,,,,,,Nerve function and healing by regulating myelin,,,,,,,,Prevent endometrial cancer by regulating effects of estrogen,,,,,,,,11,secosteroid,"Calcitriol (1,25-dihydroxyvitamin D3)",,skin/proximal tubule of kidneys,,VDR,,Active form of vitamin D3,,,,,,,,,,,,,,,,Increase absorption of calcium and phosphate from gastrointestinal tract and kidneys inhibit release of PTH12,secosteroid,Calcidiol (25-hydroxyvitamin D3),,skin/proximal tubule of kidneys,,VDR,,Inactive form of vitamin D3,,,,,,,,For other more formats kindly visit : www.downloadexcelfiles.com,,,,,,,,,,,,,,,,Original source : en.wikipedia.org/wiki/List_of_human_hormones,,,,,,,,